[생명공학] 발기부전 (ED - erectile dysfunction)
이미지출처 : thebsreport.wordpress.com
대부분 PDE5 inhibitor (phosphodiesterase 5 inhibitor) 이다.
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# erectility sequence
1. sexual stimulation
2. nitric oxide secretion on endothelium
3. guanylyl cyclase(GTP를 CGMP로 변환하는 것을 촉진시키는 효소.) activation
4. cGMP increasement
5. Ca+2 concentration decreasement
6. blood flowrate increasement
7. ejaculation